Articles published in scientific journals

     Cuklev F, Kristiansson E, Fick J, Asker N, Förlin L and Larsson DGJ (2011) Diclofenac in fish - blood plasma levels similar to human therapeutic levels affect global hepatic gene expression. Environ Toxicol Chem, in press. Abstract

     Falås P, Andersen HR, Ledin A and Jansen JC (2011) Impact of solid retention time and nitrification capacity on the ability of activated sludge to remove pharmaceuticals. Environmental Technology, in press. Abstract

     Gao K, Brandt I, Goldstone JV and Jönsson ME (2011) Cytochrome P450 1A, 1B, and 1C mRNA induction patterns in three-spined stickleback exposed to a transient and a persistent inducer. Comp Biochem Physiol C Toxicol Pharmacol 154: 42-55. Abstract

     Hansson SO, Molander L and Rudén C (2011) The substitution principle. Regul Toxicol Pharmacol 59: 454-460. Abstract

     Hey G, Ledin A, Jansen JC and Andersen HR (2011) Removal of pharmaceuticals in biologically treated wastewater by chlorine dioxide or peracetic acid. Environmental Technology, in press. Abstract

     Holmberg A, Fogel J, Albertsson E, Fick J, Brown JN, Paxéus N, Förlin L, Johnsson JI and Larsson DGJ (2011) Does waterborne citalopram affect the aggressive and sexual behaviour of rainbow trout and guppy? J Hazard Mater 187: 596-599. Abstract

     Hörsing M, Ledin A, Grabic R, Fick J, Tysklind M, Jansen JC and Andersen HR (2011) Determination of sorption of seventy-five pharmaceuticals in sewage sludge. Water Res 45: 4470-4482. Abstract

     Jönsson ME, Berg C, Goldstone JV and Stegeman JJ (2011) New CYP1 genes in the frog Xenopus (Silurana) tropicalis: induction patterns and effects of AHR agonists during development. Toxicol Appl Pharmacol 250: 170-183. Abstract

     Jönsson ME, Gao K, Olsson JA, Goldstone JV and Brandt I (2011) Induction patterns of new CYP1 genes in environmentally exposed rainbow trout. Aquat Toxicol 98: 311-321. Abstract

     Kristiansson E, Fick J, Janzon A, Grabic R, Rutgersson C, Weijdegård B, Söderström H and Larsson DGJ (2011) Pyrosequencing of Antibiotic-Contaminated River Sediments Reveals High Levels of Resistance and Gene Transfer Elements. PLoS ONE 6: e17038. Read article

     Kvarnryd M, Grabic R, Brandt I and Berg C (2011) Early life progestin exposure causes arrested oocyte development, oviductal agenesis and sterility in adult Xenopus tropicalis frogs. Aquat Toxicol 103: 18-24. Abstract

     Lennquist A, Asker N, Kristiansson E, Brenthel A, Björnsson BT, Kling P, Hultman M, Larsson DGJ and Förlin L (2011) Physiology and mRNA expression in rainbow trout (Oncorhynchus mykiss) after long-term exposure to the new antifoulant medetomidine. Comparative Biochemistry and Physiology, Part C, in press. Abstract

     Preuss TG, Brinkman M, Lundstrom E, Bengtsson BE and Breitholtz M (2011) An individual-based modeling approach for evaluation of endpoint sensitivity in harpacticoid copepod life cycle tests and optimization of test design. Environ Toxicol Chem, in press. Abstract

     Ramaswamy BR, Shanmugam G, Velu G, Rengarajan B and Larsson DGJ (2011) GC-MS analysis and ecotoxicological risk assessment of triclosan, carbamazepine and parabens in Indian rivers. J Hazard Mater 186: 1586-1593. Abstract

     Samuelsson LM, Björlenius B, Förlin L and Larsson DGJ (2011) Reproducible (1)H NMR-Based Metabolomic Responses in Fish Exposed to Different Sewage Effluents in Two Separate Studies. Environ Sci Technol 45: 1703-1710. Abstract

     Ågerstrand M, Breitholtz M and Rudén C (2011) Comparison of four different methods for reliability evaluation of ecotoxicity data - A case study of non-standard test data used in environmental risk assessments of pharmaceutical substances. Environ Sci Eur 23: 17. Read article

     Ågerstrand M, Küster A, Bachmann J, Breitholtz M, Ebert I, Rechenberg B and Rudén C (2011) Reporting and evaluation criteria as means towards a transparent use of ecotoxicity data for environmental risk assessment of pharmaceuticals. Environmental Pollution, in press. Abstract

2010

     Accinelli C, Sacca ML, Batisson I, Fick J, Mencarelli M and Grabic R (2010) Removal of oseltamivir (Tamiflu) and other selected pharmaceuticals from wastewater using a granular bioplastic formulation entrapping propagules of Phanerochaete chrysosporium. Chemosphere 81: 436-443. Abstract

     Accinelli C, Saccà ML, Fick J, Mencarelli M, Lindberg R and Olsen B (2010) Dissipation and removal of oseltamivir (Tamiflu) in different aquatic environments. Chemosphere 79: 891-897. Abstract

     Albertsson E, Larsson DGJ and Förlin L (2010) Induction of hepatic carbonyl reductase/20beta-hydroxysteroid dehydrogenase mRNA in rainbow trout downstream from sewage treatment works--possible roles of aryl hydrocarbon receptor agonists and oxidative stress. Aquat Toxicol 97: 243-249. Abstract

     Beijer K, Abrahamson A, Brunström B and Brandt I (2010) CYP1A inhibition in fish gill filaments: a novel assay applied on pharmaceuticals and other chemicals. Aquat Toxicol 96: 145-150. Abstract

     Fick J, Lindberg RH, Tysklind M and Larsson DGJ (2010) Predicted critical environmental concentrations for 500 pharmaceuticals. Regul Toxicol Pharmacol 58: 516-523. Abstract

     Fick J, Lindberg RH, Parkkonen J, Arvidsson B, Tysklind M and Larsson DGJ (2010) Therapeutic levels of levonorgestrel detected in blood plasma of fish: results from screening rainbow trout exposed to treated sewage effluents. Environ Sci Technol 44: 2661-2666. Abstract

     Larsson DGJ (2010) Release of active pharmaceutical ingredients from manufacturing sites--need for new management strategies. Integr Environ Assess Manag 6: 184-186. Abstract

     Lindberg RH, Fick J and Tysklind M (2010) Screening of antimycotics in Swedish sewage treatment plants--waters and sludge. Water Res 44: 649-657. Abstract

     Lundström E, Adolfsson-Erici M, Alsberg T, Björlenius B, Eklund B, Lavén M and Breitholtz M (2010) Characterization of additional sewage treatment technologies: ecotoxicological effects and levels of selected pharmaceuticals, hormones and endocrine disruptors. Ecotoxicol Environ Saf 73: 1612-1619. Abstract

     Strömqvist M, Tooke N and Brunström B (2010) DNA methylation levels in the 5' flanking region of the vitellogenin I gene in liver and brain of adult zebrafish (Danio rerio)--sex and tissue differences and effects of 17alpha-ethinylestradiol exposure. Aquat Toxicol 98: 275-281. Abstract

     Ågerstrand M and Rudén C (2010) Evaluation of the accuracy and consistency of the Swedish environmental classification and information system for pharmaceuticals. Sci Total Environ 408: 2327-2339. Abstract

2009

     Berg C, Gyllenhammar I and Kvarnryd M (2009) Xenopus tropicalis as a test system for developmental and reproductive toxicity. J Toxicol Environ Health A 72: 219-225. Abstract

     Fick J, Söderström H, Lindberg RH, Phan C, Tysklind M and Larsson DG (2009) Contamination of surface, ground, and drinking water from pharmaceutical production. Environ Toxicol Chem 28: 2522-2527. Abstract

     Gunnarsson L, Adolfsson-Erici M, Björlenius B, Rutgersson C, Förlin L and Larsson DG (2009) Comparison of six different sewage treatment processes--reduction of estrogenic substances and effects on gene expression in exposed male fish. Sci Total Environ 407: 5235-5242. Abstract

     Gunnarsson L, Kristiansson E, Rutgersson C, Sturve J, Fick J, Förlin L and Larsson DG (2009) Pharmaceutical industry effluent diluted 1:500 affects global gene expression, cytochrome P450 1A activity, and plasma phosphate in fish. Environ Toxicol Chem 28: 2639-2647. Abstract

     Gyllenhammar I, Holm L, Eklund R and Berg C (2009) Reproductive toxicity in Xenopus tropicalis after developmental exposure to environmental concentrations of ethynylestradiol. Aquat Toxicol 91: 171-178. Abstract

     Gyllenhammar I, Eriksson H, Söderqvist A, Lindberg RH, Fick J and Berg C (2009) Clotrimazole exposure modulates aromatase activity in gonads and brain during gonadal differentiation in Xenopus tropicalis frogs. Aquat Toxicol 91: 102-109. Abstract

     Larsson DGJ and Fick J (2009) Transparency throughout the production chain--a way to reduce pollution from the manufacturing of pharmaceuticals? Regul Toxicol Pharmacol 53: 161-163. Abstract

     Lundström E, Björlenius B, Brinkmann M, Hollert H, Persson JO and Breitholtz M (2009) Comparison of six sewage effluents treated with different treatment technologies--population level responses in the harpacticoid copepod Nitocra spinipes. Aquat Toxicol 96: 298-307. Abstract

     Molander L, Ågerstrand M and Rudén C (2009) WikiPharma - a freely available, easily accessible, interactive and comprehensive database for environmental effect data for pharmaceuticals. Regul Toxicol Pharmacol 55: 367-371. Abstract

     Saccà ML, Accinelli C, Fick J, Lindberg R and Olsen B (2009) Environmental fate of the antiviral drug Tamiflu in two aquatic ecosystems. Chemosphere 75: 28-33. Abstract

     Söderström H, Lindberg RH and Fick J (2009) Strategies for monitoring the emerging polar organic contaminants in water with emphasis on integrative passive sampling. J Chromatogr A 1216: 623-630. Abstract

     Söderström H, Järhult JD, Olsen B, Lindberg RH, Tanaka H and Fick J (2009) Detection of the antiviral drug oseltamivir in aquatic environments. PLoS One 4: e6064. Abstract

     Ågerstrand M, Wester M and Rudén C (2009) The Swedish Environmental Classification and Information System for Pharmaceuticals--an empirical investigation of the motivations, intentions and expectations underlying its development and implementation. Environ Int 35: 778-786. Abstract

2008

     Gunnarsson L, Jauhiainen A, Kristiansson E, Nerman O and Larsson DG (2008) Evolutionary conservation of human drug targets in organisms used for environmental risk assessments. Environ Sci Technol 42: 5807-5813. Abstract

     Nordberg A, Rudén C and Hansson SO (2008) Towards more efficient testing strategies--analyzing the efficiency of toxicity data requirements in relation to the criteria for classification and labelling. Regul Toxicol Pharmacol 50: 412-419. Abstract

     Samuelsson LM and Larsson DGJ (2008) Contributions from metabolomics to fish research. Mol Biosyst 4: 974-979. Abstract